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CL-7402

CL-7402

Product Overview

High Mechanical Strength: Rigid cross-linked structure, resistant to high pressure, high flow rate, and osmotic pressure shock; repeatable CIP (clean in situ) with long lifespan.

Product Details

Core Characteristics

1. • High Mechanical Strength: Rigid cross-linked structure, resistant to high pressure, high flow rate, and osmotic pressure shock; repeatable CIP (clean in situ) with long lifespan.

• High Adsorption Capacity: Large specific surface area (560 m²/g), moderate pore size, high loading capacity for peptides, oligonucleotides, and small molecule drugs.

• Wide pH/Temperature Tolerance: Stable at pH 1–14 and ≤60℃; can be regenerated using strong acid and alkali cleaning, adaptable to extreme process conditions.

• Alternative to Reversed-Phase Silica Gel: Silicon alcohol-free, metal-free, resistant to organic solvents, low cost, suitable for large-scale industrial chromatographic purification.

Typical Applications

• Biopharmaceutical Applications: Peptide Purification: Growth hormone, insulin, peptide hormones (e.g., CG71M/CG71S, high resolution).

• Oligonucleotides/Oligonucleotides: Desalting and purification (e.g., DNA/RNA fragments, antisense oligonucleotides).

• Proteins/Enzymes: Separation of medium molecular weight proteins (e.g., cytochromes, lysozyme).

• Small molecule pharmaceutical drugs: Enrichment and purification of antibiotics, flavonoids, polyphenols, and alkaloids (plant extracts).

• Chiral compounds: Assisted chiral resolution (reverse phase mode).

• Food/natural products and pigments: Extraction and purification of anthocyanins and carotenoids.

• Functional components: Enrichment of tea polyphenols, ginsenosides, and ginkgo flavonoids.

Product Parameters

Basic Information

• Matrix Structure: / Backbone: Acrylic copolymer (aliphatic, highly hydrophilic)

• Functional Groups: None (pure hydrophobic adsorption/reverse interaction)

• Appearance: Opaque white spherical particles

• Particle Size Range: Distribution (CG71C): 80–160 μm ≥80%

• Uniformity Coefficient: ≈1.7

• Specific Surface Area: ≈560 m²/g

• Average Pore Size: 250 Å (25 nm)

• Water Content: ≈60% (water/ethanol system)

• True Density: ≈1.05 g/mL

• pH Tolerance Range: Stability: 1–14 (stable across all pH levels, resistant to acids and alkalis)

• Temperature Tolerance: 60℃

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